OECD TG-121 Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC)
OECD GLP Physical-Mechanical Test
WESHIN INSPECTION TECH CO., LTD_

OECD TG 121: Estimation of the Adsorption Coefficient (Koc) on Soil and Sewage Sludge using HPLC

 

Predicting environmental mobility with precision to ensure chemical safety and water protection.
 

The mobility of a chemical in soil and its potential to leach into groundwater are primarily dictated by its adsorption coefficient Koc. At Weshin Inspection Tech, we provide high-accuracy estimation of Koc following the OECD Test Guideline 121 (TG 121) using High-Performance Liquid Chromatography (HPLC).

 

The Importance of Koc Determination

 

The organic carbon-normalized adsorption coefficient Koc is a fundamental parameter for assessing the environmental fate of organic substances:

  • Environmental Mobility Assessment: Identifying whether a substance will remain bound to soil/sludge or migrate through the soil profile into aquatic systems.

  • Regulatory Compliance:Koc is a mandatory data requirement for REACH, agrochemicals, and biocidal products registration.

  • Groundwater Protection: Providing critical data for leaching models used in environmental risk characterization.
     

Our Technical Methodology: The HPLC Method

 

The HPLC method (TG 121) offers a rapid, reliable, and cost-effective alternative to traditional batch equilibrium studies:

  • Soil Matrix Simulation: Utilizing a Cyanopropyl stationary phase column to mimic the interaction between chemicals and organic matter in soil and sludge.

  • Robust Calibration: Correlating the retention time of the test substance with a series of reference standards with known log Koc values.

  • Broad Applicability: Effectively estimating log Koc values ranging from 1.5 to 5.0, suitable for a diverse array of organic compounds.
     

Why Partner with Weshin Inspection Tech?

 

  • Analytical Excellence: Our laboratory utilizes state-of-the-art HPLC systems with precise temperature control to ensure maximum data reproducibility.

  • Validated Reference Suite: We maintain an extensive library of certified reference standards to ensure the highest accuracy of the calibration curve.

  • Audit-Ready Documentation: We deliver comprehensive technical reports featuring calibration plots, capacity factors k, and calculated log Koc values, designed for direct regulatory submission.


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