Regulatory

Ensure your chemicals' compliance and safety! Octanol/Water Partition Coefficient HPLC Testing Service

When faced with complex new chemicals, poorly soluble drugs, or high-throughput screening, are you still using the time-consuming traditional shake-flask method to measure the partition coefficient?
We offer internationally recognized High Performance Liquid Chromatography (HPLC) for determining the octanol/water partition coefficient, making your compliance journey faster and more accurate!
The octanol/water partition coefficient is a key indicator for assessing a substance's environmental behavior and toxicological properties (such as bioaccumulation, ADME (absorption, distribution, metabolism, excretion), and ecotoxicity).

Why is this test crucial?

1. Environmental and Human Safety Assessment: Directly reflects the hydrophobicity of a substance. The higher the value, the greater the likelihood of the substance accumulating in adipose tissue or environmental media (such as soil and organisms), i.e., higher bioaccumulation, and a higher potential risk to humans and ecosystems. 2. Regulatory Compliance Requirements: Many national and regional chemical management regulations (e.g., EU REACH Regulation, OECD Testing Guidelines) list this as mandatory or highly recommended data for substance classification, labeling, risk assessment, and registration. Therefore, national regulations and international organizations (e.g., ICH, OECD, FDA, EMA, REACH) explicitly stipulate that octanol/water partition coefficient (logP) data must be provided when developing chemicals, pharmaceuticals, and new ingredients.

International Compliance with HPLC Methods (Example):

Our HPLC testing services strictly adhere to internationally recognized regulatory guidelines:

We use the OECD TG 117 standardized HPLC method, establishing calibration curves using standards with known logP values ​​to ensure data accuracy and reproducibility.
Choose [Weixin Testing Technology], and we will provide reliable data support for your product safety and regulatory registration with high-precision, internationally standardized experimental methods.
Contact us now to learn how n-octanol/water partition coefficient testing can help your products successfully enter the global market!