2026-Feb-02
Make sure your chemicals are compliant and safe! n-Octanol/water partition coefficient HPLC testing service
When faced with complex new chemicals, poorly soluble drugs or high-throughput screening, are you still using the time-consuming traditional shake flask method
(Shake Flask Method) Measure partition coefficient?
We provide internationally recognized high-performance liquid chromatography (HPLC) determination of n-octanol/water partition coefficient, making your road to compliance faster
Faster and more accurate!
???? "N-Octanol/Water Partition Coefficient" is used to evaluate the environmental behavior and toxicological properties of a substance (such as bioaccumulation, ADME (absorption, etc.) distribution, metabolism, excretion) and ecotoxicity).
???? Why is this test important?
1. Environmental and human safety assessment: directly reflects the hydrophobicity of the substance. The higher the number, the more the substance is present in adipose tissue or the environment
The greater the possibility of accumulation in the medium (such as soil, organisms), that is, the higher the bioaccumulation, the greater the impact on the human body and ecosystem
The potential risk is also higher.
2. Regulatory compliance requirements: Chemical management regulations in many countries and regions (for example: EU REACH regulations, OECD
Testing Guidelines) all list this as mandatory or highly recommended data for classification, labeling, risk assessment and
Register.
Therefore, national regulations and international organizations (such as ICH, OECD, FDA, EMA, REACH) have clearly stated: chemicals, drugs
When developing products or new ingredients, n-octanol/water partition coefficient (logP) information must be provided.
???? Correspondence between international regulations and HPLC method (International Compliance) Example:
Our HPLC testing services strictly follow internationally recognized regulatory guidelines:
Regulatory Organization Corresponding Test Guidelines/Regulations Why it matters
OECD (Economic Cooperation
(Commission and Development Organization)
OECD TG 117
(HPLC Method)
Internationally recognized standard methods, data are mutually recognized around the world,
For registration of chemicals and pesticides.
European Union (EU) REACH Regulation (Annex
VII/VIII/IX/X)
Registration tonnage and risk assessment requirements, especially determining whether a substance is
Whether it has PBT (persistent, bioaccumulative, toxic) properties.
United States (US) EPA Related Guidelines Environmental Flow and Risk Assessment of Pesticides and Industrial Chemicals
Estimate.
We adopt the OECD TG 117 standardized HPLC method and use standards with known logP to establish a calibration curve to ensure data
accuracy and reproducibility.
✅ Choose [Weili Inspection Technology], we use high-precision experimental methods that comply with international standards to ensure your product safety and regulations
Registration provides reliable data support.
Contact us today to learn how n-octanol/water partition coefficient testing can help your products successfully enter the global market!
(Shake Flask Method) Measure partition coefficient?
We provide internationally recognized high-performance liquid chromatography (HPLC) determination of n-octanol/water partition coefficient, making your road to compliance faster
Faster and more accurate!
???? "N-Octanol/Water Partition Coefficient" is used to evaluate the environmental behavior and toxicological properties of a substance (such as bioaccumulation, ADME (absorption, etc.) distribution, metabolism, excretion) and ecotoxicity).
???? Why is this test important?
1. Environmental and human safety assessment: directly reflects the hydrophobicity of the substance. The higher the number, the more the substance is present in adipose tissue or the environment
The greater the possibility of accumulation in the medium (such as soil, organisms), that is, the higher the bioaccumulation, the greater the impact on the human body and ecosystem
The potential risk is also higher.
2. Regulatory compliance requirements: Chemical management regulations in many countries and regions (for example: EU REACH regulations, OECD
Testing Guidelines) all list this as mandatory or highly recommended data for classification, labeling, risk assessment and
Register.
Therefore, national regulations and international organizations (such as ICH, OECD, FDA, EMA, REACH) have clearly stated: chemicals, drugs
When developing products or new ingredients, n-octanol/water partition coefficient (logP) information must be provided.
???? Correspondence between international regulations and HPLC method (International Compliance) Example:
Our HPLC testing services strictly follow internationally recognized regulatory guidelines:
Regulatory Organization Corresponding Test Guidelines/Regulations Why it matters
OECD (Economic Cooperation
(Commission and Development Organization)
OECD TG 117
(HPLC Method)
Internationally recognized standard methods, data are mutually recognized around the world,
For registration of chemicals and pesticides.
European Union (EU) REACH Regulation (Annex
VII/VIII/IX/X)
Registration tonnage and risk assessment requirements, especially determining whether a substance is
Whether it has PBT (persistent, bioaccumulative, toxic) properties.
United States (US) EPA Related Guidelines Environmental Flow and Risk Assessment of Pesticides and Industrial Chemicals
Estimate.
We adopt the OECD TG 117 standardized HPLC method and use standards with known logP to establish a calibration curve to ensure data
accuracy and reproducibility.
✅ Choose [Weili Inspection Technology], we use high-precision experimental methods that comply with international standards to ensure your product safety and regulations
Registration provides reliable data support.
Contact us today to learn how n-octanol/water partition coefficient testing can help your products successfully enter the global market!
